VOLUME 1
Section I : Physiologic Systems
Chapter 1 : An Outline of Cardiovascular Structure and Function
Chapter 2 : Endocrine System
Chapter 3 : Nervous System
Chapter 4 : Vision System
Chapter 5 : Auditory System
Chapter 6 : The Gastrointestinal System
Chapter 7 : Respiratory System
Section II : Bioelectric Phenomena
Chapter 8 : Basic Electrophysiology
Chapter 9 : Volume Conductor Theory
Chapter 10 : The Electrical Conductivity of Tissues
Chapter 11 : Membrane Models
Chapter 12 : Numerical Methods for Bioelectric Field Problems
Chapter 13 : Principles of Electrocardiography
Chapter 14 : Principles of electromyography
Chapter 15 : Principles of Electroencephalography
Chapter 16 : Biomagnetism
Chapter 17 : Electric Stimulation of Excitable Tissue
Section III : Biomechanics
Chapter 18 : Mechanics of Hard Tissue
Chapter 19 : Mechanics of Blood Vessels
Chapter 20 : Joint-Articulating Surface Motion
Chapter 21 : Joint Lubrication
Chapter 22 : Musculoskeletal Soft Tissue Mechanics
Chapter 23 : Mechanics of Head/Neck
Chapter 24 : Biomechanics of Chest and Abdomen Impact
Chapter 25 : Analysis of Gait
Chapter 26 : Exercise Physiology
Chapter 27 : Factors Affecting Mechanics Work in Humans
Chapter 28 : Cardiac Biodynamics
Chapter 29 : Heart Valve Dynamics
Chapter 30 : Arterial Macrocirculatory Hemodynamics
Chapter 31 : Mechanics and Transport in The Microcirculation
Chapter 32 : Mechanics and Deformability of Hematocytes
Chapter 33 : The Venous System
Chapter 34 : Mechanics of Tissue/Lymphatic Transport
Chapter 35 : Cochlear Mechanics
Chapter 36 : Vestibular Mechanics
Section IV : Biomaterials
Chapter 37 : Metallic Biomaterials
Chapter 38 : Ceramic Biomaterials
Chapter 39 : Polymeric Biomaterials
Chapter 40 : Composite Biomaterials
Chapter 41 : Biodegradable Polymeric Biomaterials: An Updated Overview
Chapter 42 : Biologic Biomaterials: Tissue-Derived Biomaterials (Collagen)
Chapter 43 : Soft Tissue Replacements
Chapter 44 : Hard Tissue Replacements
Chapter 45 : Preservation Techniques for Biomaterials
Chapter 46 : Hip Joint Prosthesis Fixation-Problems and Possible Solutions
Section V : Biomedical Sensors
Chapter 47 : Physical Measurements
Chapter 48 : Biopotential Electrodes
Chapter 49 : Electrochemical Sensors
Chapter 50 : Optical Sensors
Chapter 51 : Bioanalytic Sensors
Section VI : Biomedical Signal Analysis
Chapter 52 : Biomedical Signals: Origin and Dynamic Characteristics; Frequency-Domain Analysis
Chapter 53 : Digital Biomedical Signal Acquisition and Processing
Chapter 54 : Compression of Digital Biomedical Signals
Chapter 55 : Time-Frequency Signal Representations for Biomedical Signals
Chapter 56 : Wavelet (Time-Scale) Analysis in Biomedical Signal Processing
Chapter 57 : Higher-Order Spectral Analysis
Chapter 58 : Neural Networks in Biomedical Signal Processing
Chapter 59 : Complexity, Scaling and Fractals in Biomedical Signals
Chapter 60 : Future Directions: Biomedical Signal Processing and Networked Multimedia Communications
Chapter 61 : X-Ray
Chapter 62 : Computed Tomography
Chapter 63 : Magnetic Resonance Imaging
Chapter 64 : Nuclear Medicine
Chapter 65 : Ultrasound
Chapter 66 : Magnetic Resonance Microscopy
Chapter 67 : Positron-Emission Tomography (PET)
Chapter 68 : Electrical Impedance Tomography
Chapter 69 : Medical Applications of Virtual Reality Technology
Section VIII : Medical Instruments and Devices
Chapter 70 : Biopotential Amplifiers
Chapter 71 : Noninvasive Arterial Blood Pressure and Mechanics
Chapter 72 : Cardiac Output Measurement
Chapter 73 : Bioelectric Impedance Measurements
Chapter 74 : Respiration
Chapter 75 : Clinical Laboratory: Separation and Spectral Methods
Chapter 76 : Clinical Laboratory: Nonspectral Methods and Automation
Chapter 77 : Implantable Cardiac Pacemakers
Chapter 78 : Implantable Stimulators for Neuromuscular Control
Chapter 79 : External Defibrillators
Chapter 80 : Implantable Defibrillators
Chapter 81 : Electrosurgical Devices
Chapter 82 :Mechanics Ventilation
Chapter 83 : Parenteral Infusion Devices
Chapter 84 : Essentials of Anesthesia Delivery
Chapter 85 : Biomedical Lasers
Chapter 86 : Noninvasive Optical Monitoring
Chapter 87 : Medical Instruments and Devices Used in The Home
Chapter 88 : Virtual Instrumentation
Section IX : Biologic Effects of Nonionizing Electromagnetic Fields
Chapter 89 : Dielectric Properties of Tissues
Chapter 90 : Low-Frequency Magnetic Fields: Dosimetry, Cellular, and Animal Effects
Chapter 91 : Therapeutic Applications of Low-Frequency Sinusoidal and Pulsed Electric and Magnetic Fields
Chapter 92 : Biologic Effects of Radiofrequency and Microwave Fields: In Vivo and in Vitro Experimental Results
Chapter 93 : Radio Frequency Hyperthermia in Cancer Therapy
Chapter 94 : Electroporation of Cells and Tissues
Appendix A
Index
VOLUME 2
Section X : Transport Phenomena and Biomimetic Systems
Chapter 95 : Biomimetic Systems
Chapter 96 : Diffusional Processes and Engineering Design
Chapter 97 : Animal Surrogate Systems
Chapter 98 : Microvascular Heat Transfer
Chapter 99 : Interstitial Transport in The Brain: Principles for Local Drug Delivery
Chapter 100 : Arterial Wall Mass Transport: The Possible Role of Blood Phase Resistance in the Localization of Arterial Disease
Section XI : Biotechnology
Chapter 101 : Protein Engineering
Chapter 102 : Monoclonal Antibodies and Their Engineered Fragments
Chapter 103 : Antisense Technology
Chapter 104 : Tools for Genome Analysis
Chapter 105 : Vaccine Production
Chapter 106 : Gene Therapy
Chapter 107 : Cell Engineering
Chapter 108 : Metabolic Engineering
Section XII : Tissue Engineering
Chapter 109 : Tissue Engineering
Chapter 110 : Surface Immobilization of Adhesion Ligands for Investigations of Cell-Substrate Interactions
Chapter 111 : Biomaterials: protein-Surface Interactions
Chapter 112 : Engineering Biomaterials for Tissue Engineering: The 10-100 Micron Size Scale
Chapter 113 : Regeneration Templates
Chapter 114 : Fluid Shear Stress Effects on Cellular Function
Chapter 115 : The Roles of Mass Transfer in Tissue Function
Chapter 116 : The Biology of Stem Cells
Chapter 117 : Cell Motility and Tissue Architecture
Chapter 118 : Tissue Microenvironments
Chapter 119 : The Importance of Stromal Cells
Chapter 120 : Tissue Engineering of Bone Marrow
Chapter 121 : Tissue Engineering of The Liver
Chapter 122 : Tissue Engineering in The Nervous System
Chapter 123 : Tissue Engineering in The Skeletal Muscle
Chapter 124 : Tissue Engineering of Cartilage
Chapter 125 : Tissue Engineering of The Kidney
Section XIII : Prostheses and Artificial Organs
Chapter 126 : Artificial Heart and Circulatory Assist Devices
Chapter 127 : Cardiac Valve Prostheses
Chapter 128 : Vascular Grafts
Chapter 129 : Artificial Lungs and Blood-Gas Exchange Devices
Chapter 130 : Artificial Kidney
Chapter 131 : Peritoneal Dialysis Equipment
Chapter 132 : Therepeutic Apheresis and Blood Fractionation
Chapter 133 : Liver Support Systems
Chapter 134 : Artificial Pancreas
Chapter 135 : Nerve Guidance Channels
Chapter 136 : Tracheal, Laryngeal, and Esophageal Replacement Devices
Chapter 137 : Artificial Blood
Chapter 138 : Artificial Skin and Dermal Equivalents
Section XIV : Rehabiliation Engineering
Chapter 139 : Rehabilitation Engineering, Science, and Technology
Chapter 140 : Orthopedic Prosthetics and Orthotics in Rehabilitation
Chapter 141 : Wheeled Mobility: Wheelchairs and Personal Transportation
Chapter 142 : Externally Powered and Controlled Orthotics and Prosthetics
Chapter 143 : Sensory Augmentation and Substitution
Chapter 144 : Augmentative and Alternative Communication
Chapter 145 : Measurement Tools and Processes in Rehabilitation Engineering
Chapter 146 : Rehabilitation Engineering Technologies: Principles of Application
Section XV : Human Performance Engineering
Chapter 147 : A Working Model for Human System-Task Interfaces
Chapter 148 : Measurement of Neuromuscular Performance Capacities
Chapter 149 : Measurement of Sensory-Motor Control Performance Capacities: Tracking Tasks
Chapter 150 : Measurement of Information-Processing Performance Capacities
Chapter 151 : High-Level Task Analysis: Mental Components
Chapter 152 : Task Analtsis and Decomposition: Physical Components
Chapter 153 : Human-Computer Interface Design Issues
Chapter 154 : Applications of Human Performance Measurements to Clinical Trials to Determine Therapy Effectiveness and Safety
Chapter 155 : Applications of Quantitative Assessment of Human Performance in Occupational Medicine
Chapter 156 : Human Performance Engineering Computer-Based Design and Analysis Tools
Chapter 157 : Human Performance Engineering: Challenges and Prospects for The Future
Section XVI : Physiological Modeling, Simulation, and Control
Chapter 158 : Modeling Strategies in Physiology
Chapter 159 : Compartmental Models of Physiologic Systems
Chapter 160 : Cardiovascular Model and Control
Chapter 161 : Respiratory Models andControl
Chapter 162 : Neural Networks for Physiological Control
Chapter 163 : Methods and Tools for Identification of Physiologic Systems
Chapter 164 : Autoregulating Windkessel Dynamics May Cause Low Frequency
Chapter 165 : Control of Movements
Chapter 166 : The Fast Eye Movement Control System
Section XVII : Clinical Engineering
Chapter 167 : Clinical Engineering: Evolution of a Discipline
Chapter 168 : Management and Assessment of Medical Technology
Chapter 169 : Risk Factors, Safety, and Management of Medical Equipment
Chapter 170 : Clinical Engineering program Indicators
Chapter 171 : Quality of Improvement and Team Building
Chapter 172 : A Standards Primer for Clinical Engineers
Chapter 173 : Regulatory and Assessment Agencies
Chapter 174 : Applications of Virtual Instruments in Health Care
Section XVIII : Medical Informatics
Chapter 175 : Hospital Information Systems: Their Function and State
Chapter 176 : Computer-Based Patient Records
Chapter 177 : Computer Networks in Health Care
Chapter 178 : Overview of Standards Related to The Emerging Health Care Information Infrastructure
Chapter 179 : Non-AI Decision Making
Chapter 180 : Design Issues in Developing Clinical Decision Support and Monitoring Systems
Section XIX : Artificial Intelligence
Chapter 181 : Artificial Intelligence in Medical Decision Making: History, Evolution, and Prospects
Chapter 182 : Artificial Neural Networks: Definitions, Methods, Applications
Chapter 183 : Clinical Decision Systems
Chapter 184 : Expert Systems: Methods and Tools
Chapter 185 : Knowledge Acquisition and Representation
Chapter 186 : Knowledge-Based Systems for Intelligent Patient Monitoring and Management in Critical Care Environments
Chapter 187 : Medical Terminology and Diagnosis Using Knowledge Bases
Chapter 188 : Natural Language Processing in Biomedicine
Section XX : Ethical Issues Associated With The Use of Medical Technology
Chapter 189 : Professional Ethics in Biomedical Engineering
Chapter 190 : Beneficence, Nonmaleficence, and Technological Progress
Chapter 191 : Ethical Issues of Animal and Human Experimentation in The Development of Medical Devices
Chapter 192 : Regulation of Medical Device Innovation
Appendix A
Index